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The Centre for Magnetic Resonance houses the most comprehensive range of magnetic resonance instrumentation in the southern hemisphere. This includes a Bruker 750mHz high resolution spectrometer, a Bruker S200 wholebody imaging system, a pulsed FT EPR system, two Siemens 1.5Tesla, and one 4Tesla scanners purchased jointly with a private hospital and the State's largest public hospital. The three scanners at the Wesley and Royal Brisbane Hospitals not only enhance our ability to carry out research and be able to gather cohorts large enough to validate data, but also allow us to collaborate with the hospitals in ground breaking research using MRI. The capital investment in the Centre is now approximately $A30 million, with the 4Tesla instrument being the first of its kind in Australia.

 

 

 

Grant Success

Congratulations to the following CMR staff who were successful in obtaining ARC and NHMRC funding ($4,964,250):

Idriss Blakey
Ian Brereton
Gary Cowin
Greig de Zubicaray
Marlies Friese
Graham Galloway
Heping Liu
Katie McMahon
Stephen Rose
Deming Wang
Andrew Whittaker

DPO878615 ARC: BLAKEY, I., Chirilla, T.V., Hill, D.J., Hawker, C.J. Generation of peptidomimetic surfaces for biomaterials applications. 2008: $190,000; 2009: 190,000; 2010: $180,000.

LPO882551 ARC: WHITTAKER, A.K., BLAKEY, I., LIU, H., Zimmerman, P.A.. Double exposure photoresists for the 32 and 22 nm lithographic nodes. 2008: $315,000; 2009: 192,5000; 2010: $242,500.

LE0882345: ARC Linkage Infrastructure, Equipment and Facilities. Mattingley, J.B., Cunnington, R., Hester, R.L., Bellgrove, M.A., Lipp, O.V., Wallis, G.M., BRERETON, I.M., GALLOWAY, G.J. DE ZUBICARAY, G.I., Crozier, S., Colditz, P.B., Jull, G.A., Hodges, P.W., Coltheart, M., Crain, S., Williams, M.A. A 3.0 Tesla MRI system for human cognitive neuroscience research. $650,000.

519716: NHMRC Project: Fraser, J., FRIESE, M., COWIN, G., WANG, D. GALLOWAY, G., Schibler, A. Hyperpolarized helium MRI to quantify regional lung damage and ventilation for improvement of recruitment strategy. $437,500.

510106 NHMRC Project: Piguet, O., Hodges, J., ROSE, S., Miller, L. Clinical and biological markers of disease presentation and progression in early frontotemporal dementia. $487,500.

519220 NHMRC Project: Mathias, J., Bigler, E., Bowden, S., Rosenfeld, J., Taylor, D., Vink, R., ROSE, S. Diagnostic and prognostic evaluation of diffusion tensor imaging and cognitive function after traumatic brain injury. $839,250.

496682 NHMRC Project: Wright, M., DE ZUBICARAY, G., Thompson, P., McMAHON, K. Unravelling genetic influences on the human brain. $712,500.

DP0880556: ARC. Copland, D.A., Nickels, L.A., McMAHON, K.,, Angwin, A.J. Approved neurocognitive substrates of naming facilitation in aphasia. 2008: $102,000; 2009: $130,000; 2010: $91,000.

DP0878630: Dunn, J.C., Dennis, S.J., DE ZUBICARAY, G.I. Single and dual process models of recognition memory: reconciliation of behavioural, electrophysiological, and neuroimaging data. 2008: $65,000; 2009: $65,000; 2010: $75,000.

Grand Opening

Gary Cowin and Mr Mickel

Advanced Imaging Symposium

On Tuesday 27th March, the 16.4T microimaging facility was officially commission by Queensland Minister for State Development, The Hon. John Mickel. The formalities were conducted in the AIBN seminar room and were followed by a tour of the 700 laboratory with presentations by Ian Brereton, Gary Cowin and Nyoman Kurniawan. The official party included Mr Mickel, the Vice Chancellor, Professor Hay, Professor Siddle, Professor Bartlett, Deputy Direction General State Development, Mr Brian Anker and Mrs Sallyanne Atkinson.

In conjunction with the opening, a symposium jointly organised with QBI on Molecular Imaging of the Brain was held the following day at Customs House. The highly stimulating program covered a wide range of molecular imaging and microscopy applications. Presentations were given by international speakers, Stephen Blackband (McKnight Brain Institute, Florida), Zang-Hee Cho (Neuroscience Research Institute, Gachon, Korea), and Kai-Hsiang Chuang (NIH, Bethesda). Australian presenters included David Reutens (Monash), Gary Egan (Howard Florey), Brad Moffat (Melbourne), Graham Galloway (CMR) and Linda Richards (QBI).

 

First humans trials of lung imaging to begin

The Hyperpolarised Gas group has pilot data for our first human trials of HP3He lung imaging. Images of a phantom (2 Tedlar bags filled with a mixture of HP3H3 and N2, joined by Teflon tubing and tap ware) were obtained on the S200, using a pair of linear element coils designed and made by Don Maillet.

Human lung imaging experiments are planned for June.

Brain Bee Challenge

Brain Bee Challenge

On 13th March CMR took part in welcoming several groups of students participating in the Australian Brain Bee Neuroscience Challenge at UQ.

The competition helps students learn more about the brain, and the Australian Brain Bee Challenge is the perfect introduction to a science career. Sixty-five of Queensland's brightest Year 11 students competed in the challenge. These students had been selected on merit from a national exam held last October.

Graham Galloway and Gary Cowin met the students with an introductory talk and then a tour of the S200.

 

 

 

 

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